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Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction

To study the role of the CD40-CD40 ligand interaction in the development of memory B cells and its level of action during primary antibody responses in vivo, mice were injected with a soluble CD40 fusion protein (sCD40-gamma 1), so as to block the interaction. The effects of the treatment on the pri...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191540/
https://ncbi.nlm.nih.gov/pubmed/7516404
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