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CD22 is required for formation of memory B cell precursors within germinal centers

CD22 is a BCR co-receptor that regulates B cell signaling, proliferation and survival and is required for T cell-independent Ab responses. To investigate the role of CD22 during T cell-dependent (TD) Ab responses and memory B cell formation, we analyzed Ag-specific B cell responses generated by wild...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chappell, Craig P., Draves, Kevin E., Clark, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367813/
https://ncbi.nlm.nih.gov/pubmed/28346517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174661
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