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Frequency of immunoglobulin E class switching is autonomously determined and independent of prior switching to other classes

Both, in humans and in mice, a major fraction of immunoglobulin E (IgE)- expressing B lymphocytes develops by sequential Ig class switching from IgM via IgG to IgE. This sequential class switch might have functional implications for the frequency and repertoire of IgE+ cells. Here we show that in mu...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191511/
https://ncbi.nlm.nih.gov/pubmed/8195724
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