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A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon

A number of recent studies have demonstrated that cellular responses to tumor necrosis factor (TNF) mediated by the p55 and the p75 TNF receptors are distinct. To evaluate the relative in vivo toxicities of wild-type TNF alpha (wtTNF alpha) and a novel p55 TNF selective receptor agonist, healthy, an...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191464/
https://ncbi.nlm.nih.gov/pubmed/8145037
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