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Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci
Pro and pre B cells possess the long-term capacity to proliferate in vitro on stromal cells and interleukin 7 (IL-7) and can differentiate to surface immunoglobulin (sIg+) cells upon removal of IL-7 from the cultures. A key event in this differentiation is the extensive cell loss due to apoptosis. B...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1993
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191189/ https://ncbi.nlm.nih.gov/pubmed/8376934 |
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