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Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
The nef gene product encoded by the mac239 proviral clone of simian immunodeficiency virus (SIV) markedly enhances viral replication and pathogenesis in vivo. We have used this biologically active nef isolate to examine the phenotype of Nef in retrovirally transduced human T cells in culture. SIV Ne...
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| 格式: | Artigo |
|---|---|
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
1993
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191034/ https://ncbi.nlm.nih.gov/pubmed/8098729 |
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