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Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes

During feeding by infected mosquitoes, malaria sporozoites are injected into the host's bloodstream and enter hepatocytes within minutes. The remarkable target cell specificity of this parasite may be explained by the presence of receptors for the region II-plus of the circumsporozoite protein...

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Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1993
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190997/
https://ncbi.nlm.nih.gov/pubmed/8478608
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