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Receptor editing in self-reactive bone marrow B cells

A central paradigm of immunology is clonal selection: lymphocytes displaying clonally distributed antigen receptors are generated and subsequently selected by antigen for growth or elimination. Here we show that in mice transgenic for anti-H-2Kk,b antibody genes, in which a homogeneous clone of deve...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190975/
https://ncbi.nlm.nih.gov/pubmed/8459201
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