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B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes

The ability of B cells or macrophages and dendritic cells (DC) to elicit class II-restricted T cell responses in vivo was compared using a mouse chimera model. Severe combined immunodeficient (SCID) mice (H- 2d), reconstituted either with T or T+B lymphocytes from (H-2d x H-2b) donors, were immunize...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190947/
https://ncbi.nlm.nih.gov/pubmed/8436906
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