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Heterogeneity of EAE mediated by multiple distinct T-effector subsets

Both T(H)1 and T(H)17 lymphocytes are implicated in inducing EAE. In mice lacking IFNγ, T(H)17 are assumed to be the subset responsible for inflammation induction. Here, we demonstrate that IFNγ KO mice have two additional effector subsets, one that up-regulates T(H)17-associated pro-inflammatory ge...

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Detalhes bibliográficos
Main Authors: Abromson-Leeman, Sara, Ladell, Daniel S., Bronson, Roderick T., Dorf, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190732/
https://ncbi.nlm.nih.gov/pubmed/17976744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.09.031
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