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Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

Increasing evidence supports a role for oxidative DNA damage in aging and several neurodegenerative diseases including Alzheimer's disease (AD). Attack of DNA by reactive oxygen species (ROS), particularly hydroxyl radicals, can lead to strand breaks, DNA–DNA and DNA–protein cross-linking, and...

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Autors principals: Lovell, Mark A., Markesbery, William R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190704/
https://ncbi.nlm.nih.gov/pubmed/17947327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm821
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