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Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

Increasing evidence supports a role for oxidative DNA damage in aging and several neurodegenerative diseases including Alzheimer's disease (AD). Attack of DNA by reactive oxygen species (ROS), particularly hydroxyl radicals, can lead to strand breaks, DNA–DNA and DNA–protein cross-linking, and...

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Bibliografische gegevens
Hoofdauteurs: Lovell, Mark A., Markesbery, William R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190704/
https://ncbi.nlm.nih.gov/pubmed/17947327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm821
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