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Lack of Pericytes Leads to Endothelial Hyperplasia and Abnormal Vascular Morphogenesis

The association of pericytes (PCs) to newly formed blood vessels has been suggested to regulate endothelial cell (EC) proliferation, survival, migration, differentiation, and vascular branching. Here, we addressed these issues using PDGF-B– and PDGF receptor-β (PDGFR-β)–deficient mice as in vivo mod...

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Main Authors: Hellström, Mats, Gerhardt, Holger, Kalén, Mattias, Li, Xuri, Eriksson, Ulf, Wolburg, Hartwig, Betsholtz, Christer
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190573/
https://ncbi.nlm.nih.gov/pubmed/11331305
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