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Δ(9)-Tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors

BACKGROUND AND PURPOSE: It has been suggested that the endocannabinoid system elicits neuroprotection against excitotoxic brain damage. In the present study the therapeutic potential of AM 404 on ischaemia-induced neuronal injury was investigated in vivo and compared with that of the classical canna...

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Detalhes bibliográficos
Main Authors: Zani, A, Braida, D, Capurro, V, Sala, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189998/
https://ncbi.nlm.nih.gov/pubmed/17965746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707514
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