Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

BACKGROUND AND PURPOSE: Epithelial injury contributes to lung pathogenesis. Our work and that of others have identified the phosphoinositide-3 kinase (PI3K)/Akt pathway as a vital component of survival in lung epithelia. Therefore, we hypothesized that pharmacological inhibition of PTEN, a major sup...

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Main Authors: Lai, J-P, Dalton, J T, Knoell, D L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189995/
https://ncbi.nlm.nih.gov/pubmed/17922022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707501
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