Antagonism of thromboxane receptors by diclofenac and lumiracoxib

BACKGROUND AND PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) are analgesic and anti-inflammatory by virtue of inhibition of the cyclooxygenase (COX) reaction that initiates biosynthesis of prostaglandins. Findings in a pulmonary pharmacology project gave rise to the hypothesis that certain...

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Hlavní autoři: Selg, E, Buccellati, C, Andersson, M, Rovati, G E, Ezinga, M, Sala, A, Larsson, A-K, Ambrosio, E, Låstbom, L, Capra, V, Dahlén, B, Ryrfeldt, Å, Folco, G C, Dahlén, S-E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189986/
https://ncbi.nlm.nih.gov/pubmed/17965743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707518
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