Increase in weight induced by muraglitazar, a dual PPARα/γ agonist, in db/db mice: adipogenesis/or oedema?

BACKGROUND AND PURPOSE: Muraglitazar, a dual PPARα/γ agonist, caused a robust increase in body weight in db/db mice. The purpose of the study was to see if this increase in weight was due to oedema and/or adipogenesis. EXPERIMENTAL APPROACH: The affinity of muraglitazar at PPARα/γ receptors was char...

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Detalhes bibliográficos
Main Authors: Mittra, S, Sangle, G, Tandon, R, Sharma, S, Roy, S, Khanna, V, Gupta, A, Sattigeri, J, Sharma, L, Priyadarsiny, P, Khattar, S K, Bora, R S, Saini, K S, Bansal, V S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189717/
https://ncbi.nlm.nih.gov/pubmed/17211457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707000
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