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Interleukin 1 potentiates the lethal effect of tumor necrosis factor alpha/cachectin in mice

Human rIL-1 alpha and human rIL-1 beta were examined for their ability to potentiate the lethal and hypothermic effects of mouse rTNF-alpha in mice. The LD50 of rTNF-alpha was 1.5 micrograms/mouse, whereas the LD50 of rTNF-alpha was reduced to 0.4 micrograms/mouse and 0.5 micrograms/mouse when rTNF-...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189698/
https://ncbi.nlm.nih.gov/pubmed/3290384
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