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Allelic exclusion in transgenic mice carrying mutant human IgM genes
Expression of the membrane-bound version of the human mu chain in transgenic mice results in the allelic exclusion of endogenous mouse Ig heavy chain genes (6). The secreted version of the human Ig transgene has no such effect. F1 hybrid animals that carry transgenes for both secreted and membrane-b...
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| 格式: | Artigo |
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| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
1988
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189689/ https://ncbi.nlm.nih.gov/pubmed/3133444 |
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