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Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines

After culture in IL-2, thymocytes expressing either TCR-alpha/beta or - gamma/delta acquired the ability to lyse hematopoietic and solid tumor cell targets without deliberate immunization or apparent restriction by the MHC. Moreover, TCR-alpha/beta- and TCR-gamma/delta-bearing thymic cell lines demo...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189654/
https://ncbi.nlm.nih.gov/pubmed/3500263
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