CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.

The CD3 complex found associated with the T cell receptor (TCR) is essential for signal transduction following TCR engagement. During T cell development, TCR-mediated signalling promotes the transition from one developmental stage to the next and controls whether a thymocyte undergoes positive or ne...

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Detalles Bibliográficos
Autores principales: Dave, V P, Cao, Z, Browne, C, Alarcon, B, Fernandez-Miguel, G, Lafaille, J, de la Hera, A, Tonegawa, S, Kappes, D J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169733/
https://ncbi.nlm.nih.gov/pubmed/9135151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1360
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