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CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.
The CD3 complex found associated with the T cell receptor (TCR) is essential for signal transduction following TCR engagement. During T cell development, TCR-mediated signalling promotes the transition from one developmental stage to the next and controls whether a thymocyte undergoes positive or ne...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1997
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169733/ https://ncbi.nlm.nih.gov/pubmed/9135151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1360 |
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