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Severe Intrauterine Growth Restriction Pregnancies Have Increased Placental Endoglin Levels : Hypoxic Regulation via Transforming Growth Factor-β3
Endoglin, a co-receptor for transforming growth factor (TGF)-β(1) and -β(3) is expressed in the human placenta and plays an important role in the pathogenesis of preeclampsia. Because preeclampsia is associated with hypoxia, and because TGF-β3 is overexpressed in preeclamptic pregnancies, we examine...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Investigative Pathology
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189618/ https://ncbi.nlm.nih.gov/pubmed/18156205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070640 |
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