Severe Intrauterine Growth Restriction Pregnancies Have Increased Placental Endoglin Levels : Hypoxic Regulation via Transforming Growth Factor-β3

Endoglin, a co-receptor for transforming growth factor (TGF)-β(1) and -β(3) is expressed in the human placenta and plays an important role in the pathogenesis of preeclampsia. Because preeclampsia is associated with hypoxia, and because TGF-β3 is overexpressed in preeclamptic pregnancies, we examine...

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Detalhes bibliográficos
Main Authors: Yinon, Yoav, Nevo, Ori, Xu, Jing, Many, Ariel, Rolfo, Alessandro, Todros, Tullia, Post, Martin, Caniggia, Isabella
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189618/
https://ncbi.nlm.nih.gov/pubmed/18156205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070640
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