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Capacity of unprimed CD4+ and CD8+ T cells expressing V beta 11 receptors to respond to I-E alloantigens in vivo

Self tolerance induction in the thymus is known to delete T cells expressing certain V beta TCR molecules. In particular, V beta 17a+ and V beta 11+ T cells are selectively deleted in mice expressing H-2 I-E molecules. Although this finding implies that V beta 17a+ and V beta 11+ T cells have specif...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1989
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189546/
https://ncbi.nlm.nih.gov/pubmed/2531192
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