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Ras oncogene mutation in multiple myeloma

The frequency of ras (H-, K-, and N-ras) and c-myc oncogenes was investigated in multiple myeloma (MM). By means of the polymerase chain reaction (PCR)/oligonucleotide hybridization method, DNA from 56 tumor biopsies was analyzed for the presence of activating mutations involving codons 12 and 61 of...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1989
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189505/
https://ncbi.nlm.nih.gov/pubmed/2681517
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