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Recombinant interleukin 4 suppresses the production of interferon gamma by human mononuclear cells

rIL-4 inhibits the production of IFN-gamma by PBMC stimulated with mitogens or allogeneic cells. The suppression is observed at the protein and at the mRNA level; it is dose and time dependent, and it is abolished by a neutralizing mAb to IL-4. It is suggested that the balance between the production...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189501/
https://ncbi.nlm.nih.gov/pubmed/2530302
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