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Expansion of natural killer cells but not T cells in human interleukin 2/interleukin 2 receptor (Tac) transgenic mice
Transgenic mice expressing both human IL-2 and the L chain of IL-2-R constitutively had an unusual expansion of Thy-1+/CD3-4-8- large granular lymphocytes, which bore the elevated NK activity. Unexpectedly, the transgenic mice had neither T cell expansion nor autoreactive antibodies. The increase in...
Kaydedildi:
| Materyal Türü: | Artigo |
|---|---|
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
1989
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189472/ https://ncbi.nlm.nih.gov/pubmed/2571665 |
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