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Strain dependency of B and T lymphoma development in immunoglobulin heavy chain enhancer (E mu)-myc transgenic mice

The transgenic mice were produced by injecting eggs of B6 and C3H/HeJ mice with the human E mu-myc gene. Preferential development of B lymphomas was observed in the B6 transgenic mice, whereas the C3H/HeJ transgenic mice developed mostly T lymphomas. The phenotypic activation of B lineage cells but...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1989
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189448/
https://ncbi.nlm.nih.gov/pubmed/2504875
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