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Class I MHC can present an endogenous peptide to cytotoxic T lymphocytes

Since class I MHC glycoproteins may function by "screening and selecting" degraded proteins, we wished to determine whether very short peptides made within a cell were detected and bound by MHC, and presented for T cell perusal. We show that a 22 amino acid viral sequence containing a Db-r...

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Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1989
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189441/
https://ncbi.nlm.nih.gov/pubmed/2475568
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