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Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline V kappa genes to downstream J kappa segment in a murine B cell line

A murine B cell lymphoma (38C13) was subjected to immunoselection with mAbs directed against the idiotypic determinants of its cell surface Ig. Variants emerged with altered Ig receptors containing identical heavy chains but different light chains. The functional light chain genes in these variants...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 1989
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189373/
https://ncbi.nlm.nih.gov/pubmed/2501443
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