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Active immunization against virus infections due to antigenic drift by induction of crossreactive cytotoxic T lymphocytes

We have examined whether active immunization with c13 protein, a hybrid protein of the first 81 amino acids of the viral NS1 nonstructural protein and the HA2 subunit of A/PR/8 (H1N1) hemagglutinin, could protect BALB/c mice from challenge with A/PR/8 H1 subtype virus. Mice immunized with the c13 pr...

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Bibliografiska uppgifter
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1989
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189225/
https://ncbi.nlm.nih.gov/pubmed/2466942
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