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The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters

We have constructed a panel of Abelson murine leukemia virus- transformed pre-B cells to study the organization of the mouse VH gene families. Based on the analyses of VH gene deletions on 51 chromosomes with VH gene rearrangements, we have inferred a map order of the Igh locus that holds for both t...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189169/
https://ncbi.nlm.nih.gov/pubmed/3199068
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