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VH gene family utilization is regulated by a locus outside of the VH region

We have used the RNA colony blot method to examine VH usage in colonies derived from primary splenic B cells. We found that there are strain- specific differences in the pattern of VH usage. Using parental F1, congenic, and recombinant inbred strains we demonstrate that the genetic element that caus...

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Библиографические подробности
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 1988
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188925/
https://ncbi.nlm.nih.gov/pubmed/2451707
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