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Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma

Addition of IL-4 (1,000 U/ml) to either high or low concentrations of IL-2 augmented tumor-infiltrating lymphocytes (TIL) growth from human melanoma. Weekly restimulation with irradiated tumor cells in conjunction with IL-4 allowed enhanced growth of TIL. With low-dose IL- 2 (10 U/ml) and IL-4, expa...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189149/
https://ncbi.nlm.nih.gov/pubmed/3264324
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