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Resistance of cytolytic lymphocytes to perforin-mediated killing. Lack of correlation with complement-associated homologous species restriction

CTL and NK cells resist self-mediated killing and lysis by their own pore-forming protein (PFP; perforin). Perforin, like C, lyses RBC. Efficient C-mediated lysis of RBC occurs when both C and RBC are from different species (homologous species restriction). A protective surface protein (C8-binding p...

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Библиографические подробности
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 1988
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189133/
https://ncbi.nlm.nih.gov/pubmed/3199067
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