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A calcium- and perforin-independent pathway of killing mediated by murine cytolytic lymphocytes
Cytotoxic T lymphocytes have been thought to lyse cellular targets in the past by a calcium-dependent pathway. This notion was recently supported by the identification and purification of a pore-forming protein (perforin) from the granules of these cell types. Here, we show that perforin is absent f...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1987
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188780/ https://ncbi.nlm.nih.gov/pubmed/3500267 |
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