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A calcium- and perforin-independent pathway of killing mediated by murine cytolytic lymphocytes

Cytotoxic T lymphocytes have been thought to lyse cellular targets in the past by a calcium-dependent pathway. This notion was recently supported by the identification and purification of a pore-forming protein (perforin) from the granules of these cell types. Here, we show that perforin is absent f...

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Dettagli Bibliografici
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188780/
https://ncbi.nlm.nih.gov/pubmed/3500267
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