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Alternative V kappa gene rearrangements in a murine B cell lymphoma. An explantation for idiotypic heterogeneity

Idiotype variants of 38C13, a murine B cell lymphoma, have been isolated by immunoselection with antiidiotype mAbs. The V region genes for the kappa light chains and mu heavy chains expressed by these tumor cells were sequenced and compared. There was no evidence for V region somatic point mutation...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189115/
https://ncbi.nlm.nih.gov/pubmed/3141553
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