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Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans

Isogenic mutant strains of V. cholerae O1 lacking elements of a genetic regulon controlled by toxR and implicated in virulence were tested in volunteers. A deletion mutation in ctxA, the gene encoding the A subunit of cholera toxin, markedly attenuated disease symptoms without affecting intestinal c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 1988
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189073/
https://ncbi.nlm.nih.gov/pubmed/2902187
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