Cargando...

Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans

Isogenic mutant strains of V. cholerae O1 lacking elements of a genetic regulon controlled by toxR and implicated in virulence were tested in volunteers. A deletion mutation in ctxA, the gene encoding the A subunit of cholera toxin, markedly attenuated disease symptoms without affecting intestinal c...

Descrición completa

Gardado en:
Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1988
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189073/
https://ncbi.nlm.nih.gov/pubmed/2902187
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!