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Inactivation of a T cell receptor-associated GTP-binding protein by antibody-induced modulation of the T cell receptor/CD3 complex

TCR modulation induced by anti-TCR or anti-CD3 mAbs leads to a transient state of refractoriness of the T cell to all signals given via cell surface structures. To investigate the underlying mechanisms, we have used human CTL permeabilized with the alpha toxin of S. aureus. This method of permeabili...

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Dettagli Bibliografici
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189006/
https://ncbi.nlm.nih.gov/pubmed/2970522
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