Loading...
Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q
Humanized antibodies are likely to have a major role in therapy and it is important to define their interaction with physiological effectors. By comparing a matched series of chimeric human mAbs we found that igG1 was most efficient in complement lysis, although IgG3 bound more C1q. To resolve this...
Na minha lista:
| Format: | Artigo |
|---|---|
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
1988
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188986/ https://ncbi.nlm.nih.gov/pubmed/3260935 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|