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Peptides bound to proteosomes via hydrophobic feet become highly immunogenic without adjuvants
Addition of either a lauroyl or a pentapeptide (FLLAV) hydrophobic foot to the NH2 terminus of a small, synthetic peptide allowed the peptide to hydrophobically complex to meningococcal outer membrane protein proteosomes by simple dialysis. Both conventional and LPS- hyporesponsive mice immunized wi...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188847/ https://ncbi.nlm.nih.gov/pubmed/3346624 |
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