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The T alpha 2 nuclear protein binding site from the human T cell receptor alpha enhancer functions as both a T cell-specific transcriptional activator and repressor

T cell-specific expression of the human T cell receptor alpha (TCR- alpha) gene is regulated by the interaction of variable region promoter elements with a transcriptional enhancer that is located 4.5 kb 3' of the TCR-alpha constant region (C alpha) gene segment. The minimal TCR- alpha enhancer...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188681/
https://ncbi.nlm.nih.gov/pubmed/2230652
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