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Failure of clonal deletion in neonatally thymectomized mice: tolerance is preserved through clonal anergy
Self-tolerance is achieved in part through intrathymic deletion of self- reactive T cells. The necessity of the thymus for this process is suggested by the development of autoimmune diseases in neonatally thymectomized (neoTx) mice and by the failure of clonal deletion in nude mice. Indeed, the pres...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188676/ https://ncbi.nlm.nih.gov/pubmed/2230642 |
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