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Failure of clonal deletion in neonatally thymectomized mice: tolerance is preserved through clonal anergy

Self-tolerance is achieved in part through intrathymic deletion of self- reactive T cells. The necessity of the thymus for this process is suggested by the development of autoimmune diseases in neonatally thymectomized (neoTx) mice and by the failure of clonal deletion in nude mice. Indeed, the pres...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188676/
https://ncbi.nlm.nih.gov/pubmed/2230642
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