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The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface

We constructed expression vectors coding for the two pre-B-specific genes, VpreB and lambda 5, and transfected them together with a mu vector (mu tm) into Ig- myeloma cells. In a transfectant expressing all three introduced genes, the mu tm chain is transported on the cell surface. A biochemical ana...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188549/
https://ncbi.nlm.nih.gov/pubmed/2117639
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