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Transfer of human systemic lupus erythematosus in severe combined immunodeficient (SCID) mice
To study the role of peripheral blood leukocytes (PBL) in the pathogenesis of human systemic lupus erythematosus (SLE), we transferred PBL from 5 SLE patients into 15 severe combined immunodeficiency (SCID) mice. Such reconstituted mice showed long-term presence of auto-antibodies characteristic of...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1990
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188548/ https://ncbi.nlm.nih.gov/pubmed/2388039 |
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