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Transfer of human systemic lupus erythematosus in severe combined immunodeficient (SCID) mice

To study the role of peripheral blood leukocytes (PBL) in the pathogenesis of human systemic lupus erythematosus (SLE), we transferred PBL from 5 SLE patients into 15 severe combined immunodeficiency (SCID) mice. Such reconstituted mice showed long-term presence of auto-antibodies characteristic of...

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Bibliografske podrobnosti
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1990
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188548/
https://ncbi.nlm.nih.gov/pubmed/2388039
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